What finding is associated with higher mortality risk if hemorrhage occurs after thrombolysis?

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Multiple Choice

What finding is associated with higher mortality risk if hemorrhage occurs after thrombolysis?

Explanation:
After thrombolysis, if a hemorrhage occurs, the key sign that mortality risk is higher is a clinical worsening in neurological function. An increase in the NIHSS by a small but meaningful amount (around 2–4 points) reflects deterioration due to hemorrhagic transformation and correlates with worse outcomes, including higher mortality. This contrasts with a stable exam, normal imaging, or improved level of consciousness, which suggest there is no symptomatic bleed driving additional brain injury, and these scenarios do not carry the same elevated risk.

After thrombolysis, if a hemorrhage occurs, the key sign that mortality risk is higher is a clinical worsening in neurological function. An increase in the NIHSS by a small but meaningful amount (around 2–4 points) reflects deterioration due to hemorrhagic transformation and correlates with worse outcomes, including higher mortality. This contrasts with a stable exam, normal imaging, or improved level of consciousness, which suggest there is no symptomatic bleed driving additional brain injury, and these scenarios do not carry the same elevated risk.

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